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. 2012 Sep 12;7(9):e45063. doi: 10.1371/journal.pone.0045063

Figure 2. Ki-67 and Eag1 are transcriptionally downregulated by calcitriol and astemizole in breast cancer cells.

Figure 2

The gene expression of Ki-67 (dark circle) and Eag1 (white circle) was downregulated by calcitriol (A–B) and astemizole (C–D) in IDC-1 (A, C) and SUM-229PE cells (B, D). Eag1 was not regulated by astemizole in SUM-229PE (data not shown). Relative Ki-67 and Eag1 mRNA levels were obtained by normalizing against GAPDH mRNA expression. Vehicle values were set to one. N = at least 3, *P<0.05 vs control.