Table 5. Growth inhibitory effects (%) exerted by astemizole and calcitriol alone or in combination (C + A) using drug concentrations below the IC20 values.
Cell line | Astemizole | Calcitriol | C + A |
SUM-229PE | 3.26±0.273 | 1.94±6.31 | 34.87±4.43* |
IDC-2 | 49.60±6.98 | 10.17±0.396 | 59.09±5.27* |
Results are expressed as the mean ± S.D. percent growth inhibition. *P<0.05 vs. each drug alone, n = 6. Concentrations used were: Astemizole: 1 µM; Calcitriol: 0.1 nM and 0.01 nM for SUM-229PE and IDC-2, respectively.