Table 2. The XRCC1 Arg194Trp and Arg280His polymorphisms on CC risk.
Variables | Na | Subgroup | OR (95%CI) | Pooled methods | P b–heterogeneity P value | P–Publication bias | |||
Beggc | Eggerd | ||||||||
Arg194Trp C/T | |||||||||
Trp/Trp vs Arg/Arg | 5 | All | 2.21(1.60,3.06) | Fixed M-H method | 0.53 | 0.000 | 0.73 | 0.64 | |
Arg/Trp vs Arg/Arg | 5 | All | 1.23(1.02,1.49) | Fixed M-H method | 0.39 | 0.03 | 0.31 | 0.15 | |
Dominant | 5 | All | 1.36(1.14,1.63) | Fixed M-H method | 0.71 | 0.001 | 1.00 | 0.63 | |
Recessive | 5 | All | 2.06(1.51,2.82) | Fixed M-H method | 0.54 | 0.000 | 0.73 | 0.73 | |
Arg280His G/A | |||||||||
His/His vs Arg/Arg | 2 | All(Asian) | 1.60(0.74,3.44) | Fixed M-H method | 0.18 | 0.23 | 1.00 | NA | |
Arg/His vs Arg/Arg | 2 | All(Asian) | 1.03(0.81,1.32) | Fixed M-H method | 0.82 | 0.81 | 1.00 | NA | |
Dominant | 2 | All(Asian) | 1.07(0.84,1.36) | Fixed M-H method | 0.37 | 0.58 | 1.00 | NA | |
Recessive | 2 | All(Asian) | 1.59(0.74,3.41) | Fixed M-H method | 0.18 | 0.24 | 1.00 | NA |
NA, not application.
Number of comparisons.
P value of Q-test for heterogeneity test. Random-effects model was used when P value for heterogeneity test <0.1; otherwise, fixed-effects model was used.
P of Begg, P value of Begg rank correlation method for testing publication bias.
P of Egger, P value of Egger rank correlation method for testing publication bias.