Table 4. Quantitative analyses for the relationships between XRCC1polymorphisms and cervical cancer(CC) risk based on adjusted OR (95%CI).
Genetic | Comparisons | Sample size | Adjusted OR | Pz-test | Pheterogeneity | Model | |
polymorphisms | Na | Case/Control | (95%CI) | ||||
XRCC1 Arg399Gln | Gln/Gln vs. Arg/Arg | 6 | 1.23(0.94,1.61) | 0.127 | 0.012 | Random | |
(Total) | Arg/Gln vs. Arg/Arg | 6 | 1.04(0.74,1.45) | 0.843 | 0.001 | Random | |
Gln/Gln+Arg/Gln vs. Arg/Arg | 6 | 1.06(0.76,1.48) | 0.736 | 0.000 | Random | ||
XRCC1 Arg399Gln | Gln/Gln vs. Arg/Arg | 5 | 1.34(1.01,1.78) | 0.046 | 0.017 | Random | |
(Asian) | Arg/Gln vs. Arg/Arg | 5 | 1.29(1.11,1.50) | 0.001 | 0.276 | Fixed | |
Gln/Gln+Arg/Gln vs. Arg/Arg | 5 | 1.25(0.98,1.59) | 0.078 | 0.054 | Random | ||
XRCC1 Arg194Trp | Trp/Trp vs. Arg/Arg | 3 | 2.15(1.53,3.04) | 0.000 | 0.372 | Fixed | |
(Total) | Arg/Trp vs. Arg/Arg | 3 | 1.19(0.97,1.46) | 0.106 | 0.338 | Fixed | |
Trp/Trp+Arg/Trp vs. Arg/Arg | 3 | 1.33(1.09,1.61) | 0.004 | 0.606 | Fixed |