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. 2012 Sep 12;7(9):e44333. doi: 10.1371/journal.pone.0044333

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© 2012 Wu et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

The NVP EC₅₀ of CRF07_BC virus variants with different mutations were shown. TZM-bl cells were infected with virus variants and treaded with serial diluted NVP. After 48 hrs incubation, luciferase activities representing HIV infection were tested. The EC₅₀ NVP was estimated from the standard curve plotted by the percentage of reduction of luciferase activity and serial concentrations of NVP.