Table 2. Mutations developed in RT gene of CRF07_BC strain CNGZD during the in vitro selection with increasing concentrations of NVP.

NVP associated mutations predicted by HIVdb program
	98	106	108	135	181	189	238
B, C, CRF07_BC cons	A	V	V	I	Y	V	K
NVP	G	M	I	T	C	I	N
Novel mutations
	4	48	178	314	382	386
B, C, CRF07_BC cons	P	S,T	I	V	I	T
NVP	H	I	M	A	L/V	A

The conserved amino acid at position 48 of subtype B is S while that in subtype C and CNGZD is T.