Table 4. Comparison of drug-resistant effects between reported mutations selected in this study and those in HIV drug resistance database of Stanford University.
Drug | Mutations | Level of resistance (increased folds of EC50) | |
In this study | In HIV drug resistance database of Stanford University | ||
NVP | A98G | M (17) | L (2–3) |
V106M | H (22–32) | H (70) | |
V108I | L (3) | L (UD) | |
Y181C | H (450) | H (123) | |
K238N | L | Unknown |
H: high level of resistance (Fold change (FC)>20); M: medium level of resistance (20>FC>4); L: low level of resistance (FC<4). UD: undetected. They were defined according to Stanford database http://hivdb.stanford.edu/cgi-bin/Marvel.cgi.