Table 3. Top discriminating urine metabolites.

Importance	Compound	2Log Cold/Heatc
1	C8∶1 acylcarnitineb	−0.73
3	C10∶3 acylcarnitineb	−0.70
11	C8+OH acylcarnitineb	−0.89
13	acetylcarnitinea	−0.75
15	riboflavina	−2.40
16	C11∶1 acylcarnitineb	−0.98
21	pantothenic acida	−0.92
27	C6:DC acylcarnitineb	−0.55
31	C5 acylcarnitineb	−1.21
32	C10∶2 acylcarnitineb	−0.53
38	C8∶2 acylcarnitineb	−1.19
41	C10∶1 acylcarnitineb	−0.23
45	C9∶3 acylcarnitineb	−2.26
49	C10∶3 acylcarnitine isotopeb	−0.66
50	C6∶2:DC acylcarnitineb	0.42

^averified with authentic standard.

^bverified with characteristic 59 neutral loss, retention time order, accurate mass.

^cCalculated 2Log of the ratio between average levels in Cold and Heat patients.