Table 4.
Likelihood of oral contraceptive continuation among young women with depressed mood, perceived stress and oral contraceptive-related side effects
| Independent predictors of oral contraceptive continuation | OR | 95% CI | p-value |
|---|---|---|---|
| Depressed mood (CES-D Score ≥ 16pts) | 0.54 | 0.29–0.99 | 0.05 |
| Perceived mtress (PSS-10 Score ≥ 21pts) | 0.48 | 0.25–0.91 | 0.03 |
| Mood changes (yes/no) | 0.93 | 0.55–1.57 | 0.80 |
| Type of mood change (more, less, none) None vs more (n = 267 vs 73) None vs less (n = 267 vs 14) |
1.10 0.30 |
0.64–1.91 0.06–1.40 |
0.73 0.13 |
| Severity of mood change (none, little, some, lot) None vs little (n = 267 vs 43) None vs some (n = 267 vs 23) None vs lot (n = 267 vs 21) |
1.62 0.50 0.68 |
0.82–3.21 0.14–1.14 0.25–1.88 |
0.17 0.09 0.46 |
| Quality of mood change (none, good, bad) None vs good (n = 267 vs 18) None vs bad (n = 267 vs 41) |
0.48 1.05 |
0.16–1.45 0.52–2.13 |
0.19 0.89 |
| Attribution of mood change
(pill vs. other/no change) (n = 40 vs 314) |
1.14 |
0.56–2.33 |
0.71 |
| Weight changes (yes/no) | 0.60 | 0.38–0.94 | 0.03 |
| Type of weight change (none, gain, loss) None vs gain (n = 154 vs 135) None vs loss (n = 154 vs 65) |
0.60 0.60 |
0.36–0.99 0.31–1.14 |
0.04 0.12 |
| Severity of weight change (none, little, some, lot) None vs little (n = 154 vs 104) None vs some (n = 154 vs 44) None vs lot (n = 154 vs 52) |
0.63 0.67 0.47 |
0.37–1.09 0.32–1.42 0.23–0.97 |
0.10 0.30 0.04 |
| Quality of weight change (none, good, bad) None vs good (n = 154 vs 67) None vs bad (n = 154 vs 79) |
1.00 0.74 |
0.55–1.83 0.42–1.32 |
1.00 0.31 |
| Attribution of weight change (pill vs. other/no change) (n = 102 vs 252) |
0.97 |
0.59–1.60 |
0.90 |
| aEducation (number of grades completed) | 1.18 | 1.04–1.33 | 0.01 |
|
aBMI: Normal weight vs overweight Normal weight vs obese |
1.28 1.39 |
0.75–2.16 0.67–2.89 |
0.36 0.37 |
Center for Epidemiologic Studies – Depression Scale (CES-D); Perceived Stress Scale - 10 (PSS-10). BMI = body mass index by: normal/underweight (BMI < 25), overweight (BMI 25–29.9) and obese (BMI > 30). Results shown are from multiple logistic regression models with each psychological and side effect variable entered separately into models; point estimates were stable in combined models with all variables entered together. Results are presented as adjusted odds ratios (OR) with 95% confidence intervals (CI) based upon logistic regression. P-values for alpha <0.05 or <0.01 considered significant. Randomization treatment group was included in all models and was highly significant at alpha <0.001.
Point estimates of covariates education and BMI shown are those from the depressed mood model but were stable among all models.