Table 2.

Comparison between the acute cerebral metabolic response to citalopram in men compared to women.

Regions of greater increase in Women than Men
Right Hemisphere				Brain Region	Left Hemisphere
Talairach Coordinates					Talairach Coordinates
x (mm)	y (mm)	z (mm)	Z score		x (mm)	y (mm)	z (mm)	Z score
0	−22	33	3.54**	Anterior Cingulate	−20	41	−6	4.0*
				Medial Frontal Gyrus	−20	52	−3	3.76*
55	15	7	3.44**	Precentral Gyrus
40	−25	14	3.14	Transverse Temporal Gyrus
				Supramarginal Gyrus	−48	−44	35	3.15*
				Inferior Parietal Lobule	−60	−36	25	3.65**

Regions of greater decrease in Women than Men
Right Hemisphere				Brain Region	Left Hemisphere
Talairach Coordinates					Talairach Coordinates
x (mm)	y (mm)	z (mm)	Z score		x (mm)	y (mm)	z (mm)	Z score
12	−45	−31	3.33	Cerebellum (Anterior Lobe)
16	−63	−40	3.49	Cerebellum (Posterior Lobe)