Table I.

Correlation of p-STAT3, p-mTOR and EGFR expression with clinicopathological factors.

	n	Nuclear p-STAT3			Cytoplasmic p-mTOR			Membranous EGFR			Co-expression values
		Negative	Positive	p-value	Negative	Positive	p-value	Negative	Positive	p-value	0	1	2	3	p-value
Age
≥70	41	19	22	0.050	12	29	0.290	26	15	0.220	6	13	13	9	0.140
<70	85	55	30		33	52		63	22		22	29	27	7
Gender
Male	88	54	34	0.360	31	57	0.860	60	28	0.480	21	27	28	12	0.760
Female	38	20	18		14	24		29	9		7	15	12	4
Tumor location
Middle/Lower	103	61	42	>0.990	39	64	0.410	72	31	0.900	23	35	33	12	0.900
Upper	23	13	10		6	17		17	6		5	7	7	4
Histopathology
Intestinal	48	32	16	0.160	29	49	0.660	35	13	0.660	10	21	11	6	0.210
Diffuse	78	42	36		16	32		54	24		18	21	29	10
Depth of invasion
T1	49	39	10	<0.001	23	26	0.036	45	4	<0.001	19	20	10	0	<0.001
T2/3/4	77	35	42		22	55		44	33		9	22	30	16
LN metastasis
Negative (N0)	59	42	17	0.008	27	32	0.027	49	10	0.007	22	19	14	4	0.001
Positive (N1/2/3)	67	32	35		18	49		40	27		6	23	26	12
Distant metastasis or recurrence
Negative	88	60	28	0.001	35	53	0.210	67	21	0.039	26	30	24	8	0.008
Positive	38	14	24		10	28		22	16		2	12	16	8
Stage
I	63	47	16	<0.001	28	35	0.041	54	9	<0.001	24	21	15	3	<0.001
II/III/IV	63	27	36		17	46		35	28		4	21	25	13