Table II.
Prognostic factors in a multivariate Cox proportional hazards regression model.
| DSS
|
|||
|---|---|---|---|
| HR | 95% CI | p-value | |
| Main tumor location | |||
| Middle/Lower | 1.00 | ||
| Upper | 1.40 | 0.58-3.4 | 0.450 |
| Histopathology (Lauren) | |||
| Intestinal | 1.00 | ||
| Diffuse | 1.30 | 0.55-3.0 | 0.570 |
| Tumor depth | |||
| T1 | 1.00 | ||
| T2–4 | 3.70 | 0.75-18 | 0.110 |
| Lymph node metastasis | |||
| Negative (N0) | 1.00 | ||
| Positive (N1–3) | 1.90 | 0.67-5.7 | 0.220 |
| Distant metastasis | |||
| Negative (M0) | 1.00 | ||
| Positive (M1) | 6.40 | 2.20-19 | 0.001 |
| EGFR | |||
| Negative | 1.00 | ||
| Positive | 1.70 | 0.74-3.8 | 0.220 |
| p-mTOR | |||
| Negative | 1.00 | ||
| Positive | 0.66 | 0.26-1.7 | 0.390 |
| p-STAT3 | |||
| Negative | 1.00 | ||
| Positive | 2.00 | 0.91-4.5 | 0.082 |