Table IX.
A, Genes strongly suggested to be associated with hypertension | |||||
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Fold changes (hydralazine/none) | Strains | Clones | GB account | Description | |
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1.a | 9.646 | 6W M-SHRSP | A_44_P566390 | TC550463 | Farnesyl pyrophosphate synthetase |
2.a | 9.551 | 6W M-SHRSP | A_44_P623610 | TC525804 | Unknown |
3.a | 8.615 | 6W M-SHRSP | A_43_P10474 | TC527985 | Unknown |
4.a | 8.419 | 6W M-SHRSP | A_44_P808679 | TC541828 | Unknown |
5.a | 8.387 | 6W M-SHRSP | A_44_P104687 | Kcnc3 | Potassium voltage-gate channel protein |
6.a | 2.044 | 6W SHRSP | A_44_P871211 | TC566645 | Unknown |
7.a | 0.664 | 9W SHR | A_44_P732488 | TC567669 | Unknown |
8. | 2.367 | 6W SHR | |||
2.529 | 6W SHRSP | A_42_P811256 | Vnn1 | Participate in an oxidative-stress response | |
9. | 2.205 | 6W SHRSP | |||
8.872 | 6W M-SHRSP | A_44_P854454 | TC543180 | Unknown | |
10. | 1.260 | 9W SHR | |||
2.115 | 6W SHRSP | A_44_P435955 | RGD1561143_predicted | Similar to cell surface receptor FDFACT | |
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B, Genes possibly suggested to be associated with hypertension | |||||
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1.b | 9.245 | 6M M-SHRSP | A_44_P610417 | TC560558 | FK506-binding protein 1B |
2.c | 8.997 | 6W M-SHRSP | A_44_P841829 | TC564079 | CG4187-PA, Drosophila melanogaster |
3.b | 8.969 | 6W M-SHRSP | A_44_P917243 | TC533180 | Unknown |
4.b | 8.533 | 6W M-SHRSP | A_44_P408114 | XM_343516 | Similar to sulfotransferase K2 |
More highly expressed at 9 than at 6 weeks of age in either SHR or SHRSP;
More highly expressed at 9 than at 6 weeks of age in SHRSP;
More highly expressed at 9 than at 6 weeks of age in SHR.