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. 2011 Jun 14;2(5):963–967. doi: 10.3892/etm.2011.284

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Figure 3. — EZH2 is regulated by miR-101 in lung cancer cells. (A) Effect of miR-101 on EZH2 expression in lung cancer cells (A549, H522 and HCC1438). (B) Effect of miR-101 on CDH1 and MMP-2 expression in lung cancer cells (HCC1438). (C) Chromatin immunoprecipitation (ChIP) assay of the trimethyl H3K27 histone mark after miR-101 precursor transfection was performed in A549 cells. ChIP was performed to test H3K27 trimethylation at the promoter of CDH1. Results show the means ± standard deviation (SD) of three independent experiments performed in triplicate. ^*p<0.05 vs. control.

Figure 3. — EZH2 is regulated by miR-101 in lung cancer cells. (A) Effect of miR-101 on EZH2 expression in lung cancer cells (A549, H522 and HCC1438). (B) Effect of miR-101 on CDH1 and MMP-2 expression in lung cancer cells (HCC1438). (C) Chromatin immunoprecipitation (ChIP) assay of the trimethyl H3K27 histone mark after miR-101 precursor transfection was performed in A549 cells. ChIP was performed to test H3K27 trimethylation at the promoter of CDH1. Results show the means ± standard deviation (SD) of three independent experiments performed in triplicate. ^*p<0.05 vs. control.