Table III.
Diagnostic rates of reduction-%LMR according to cutoff value for differentiation of Child-Pugh class A and class B/C.
| Diagnostic rate (95% confidence interval)
|
||||||
|---|---|---|---|---|---|---|
| Variablea | Liver cirrhosis (n=30) | P-valueb | Sensitivity | Specificity | PPV | NPV |
| Reduction-%LMR | ||||||
| < −50% | 16 | <0.001 | 0.79 (0.54–0.94) | 0.91 (0.59–0.99) | 0.94 (0.70–0.99) | 0.71 (0.42–0.92) |
| ≥50% | 14 | |||||
PPV, positive predictive value; NPV, negative predictive value for determination of malignancy.
a
A receiver operating characteristic curve was used to select the best cutoff points.
b
Based on results of generalized estimating equation analysis of the association between the severity of liver cirrhosis and values of reduction percentages of liver-to-muscle signal intensity ratio (reduction-%LMR). If the reduction-%LMR is less than −50%, the liver cirrhosis is considered Child-Pugh class B or C.