Table I.
Baseline characteristics of the studies included in the meta-analysis.
| First author (ref.) | Year | Country | Ethnicity | Source of controls | Source of cases | Detection method | No. of subjects
|
Gender (male/female)
|
Age, in years (mean±SD)
|
|||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | Cases | Controls | Cases | Controls | |||||||
| Tzanakis, et al (28) | 2006 | Greece | Caucasian | Population-based | Hospital-based | PCR-RFLP | 100 | 100 | 58/42 | - | 65.0±12.3 | - |
| Chae, et al (29) | 2006 | Korea | Asian | Population-based | Hospital-based | PCR-RFLP | 413 | 413 | 313/100 | 333/80 | 60.2±10.3 | 60.2±9.0 |
| Bae, et al (30) | 2008 | Korea | Asian | Population-based | Hospital-based | PCR-RFLP | 154 | 229 | 91/63 | 112/117 | 58.1±12.7 | 59.6±11.8 |
| Ke, et al (31) | 2008 | China | Asian | Population-based | Population-based | PCR-RFLP | 540 | 561 | 371/169 | 384/177 | 60.4±9.5 | 59.5±10.2 |
| Al-Moundhri, et al (32) | 2009 | Oman | Caucasian | Population-based | Hospital-based | PCR-RFLP | 130 | 130 | 75/55 | - | 56.8±12.2 | 41.3±11.6 |
| Guan, et al (33) | 2009 | USA | Caucasian | Population-based | Hospital-based | PCR-RFLP | 171 | 353 | 56/115 | 104/249 | 59.7±12.6 | 57.6±11.2 |
| Tahara, et al (34) | 2009 | Japan | Asian | Hospital-based | Hospital-based | PCR-RFLP | 385 | 459 | 271/114 | 267/192 | 65.5±11.0 | 61.5±13.0 |
| Xia, et al (35) | 2010 | China | Asian | Population-based | Hospital-based | - | 238 | 425 | 191/47 | 336/89 | 61.0±9.4 | 60.6±8.4 |
PCR-RFLP, polymerase chain reaction-restriction fragment length polymorphism; SD, standard deviation.