Table III.
Association of pSTAT3 and SOCS3 expression with clinicopathological parameters of the HCC patients.
Parameter | No. | pSTAT3 expression, n (%) | P-value | SOCS3-positive expression, n (%) | P-value |
---|---|---|---|---|---|
Age (years) | 0.133 | 0.967 | |||
≤55 | 86 | 51 (59.3) | 40 (46.5) | ||
>55 | 52 | 24 (46.2) | 24 (46.2) | ||
Gender | 0.252 | 0.222 | |||
Male | 115 | 60 (52.2) | 56 (48.7) | ||
Female | 23 | 15 (65.2) | 8 (34.8) | ||
Cirrhosis | 0.533 | 0.986 | |||
Yes | 125 | 69 (55.2) | 58 (46.4) | ||
No | 13 | 6 (46.2) | 6 (46.2) | ||
HBsAg | 0.888 | 0.513 | |||
Yes | 111 | 60 (54.1) | 53 (47.7) | ||
No | 27 | 15 (55.6) | 11 (40.7) | ||
Tumor size (cm) | 0.001 | 0.137 | |||
<5 | 41 | 13 (31.7) | 23 (56.1) | ||
≥5 | 97 | 62 (63.9) | 41 (42.3) | ||
Grade | 0.417 | 0.299 | |||
I | 5 | 4 (80.0) | 4 (80.0) | ||
II | 128 | 69 (53.9) | 58 (45.3) | ||
III | 5 | 2 (40.0) | 2 (40.0) | ||
Stage | 0.002 | 0.251 | |||
I–II | 106 | 50 (47.2) | 52 (49.1) | ||
III–IV | 32 | 25 (78.1) | 12 (37.5) | ||
Ki67 | 0.000 | 0.034 | |||
<50% | 60 | 22 (36.7) | 34 (56.7) | ||
≥50% | 78 | 53 (67.9) | 30 (38.5) | ||
VEGF | 0.001 | 0.001 | |||
Negative | 53 | 12 (22.6) | 37 (69.8) | ||
Positive | 85 | 63 (74.1) | 27 (31.8) |