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. Author manuscript; available in PMC: 2012 Dec 21.
Published in final edited form as: Nature. 2012 Apr 18;486(7403):346–352. doi: 10.1038/nature10983

Figure 1. Germline and somatic variants influence tumour expression architecture.

Figure 1

a, Venn diagrams depict the relative contribution of SNPs, CNVs and CNAs to genome-wide, cis and trans tumour expression variation for significant expression associations (Šidák adjusted P-value ≤0.0001).

b, Histograms illustrate the proportion of variance explained by the most significantly associated predictor for each predictor type, where several of the top associations are indicated.