Table 2.

Comparisons of immunological and histological findings between primary SS and HCV-related SS.

Variable	Primary SS	HCV-related SS
Autoantibodies	High frequency of ANA, anti-Ro, and anti-La	Low frequency of ANA, anti-Ro, and anti-La
Cryoglobulin	Rare	Common
Hypocomplementemia	Rare	Common
Lymphocytic capillaritis	Moderate to severe	Mild to moderate
Th1/Th2 balance	Th1 predominant	Th2 predominant
Monoclonal gammopathy	Low	High
Association of HLA DR-3	High	Low