Table 3. Classification of thyroid cytology (12).
Finding | Criteria |
Inadequate | Material containing few or no thyrocytes from solid or partly liquid nodules (exception: colloid nodules) |
Negative | Any or all of the changes found in normal and hyperplastic thyroid glands (follicular adenomas with large- and mid-sized follicles),including regressive changes, cysts, and hemorrhagic (pseudo-)cysts, colloid nodules, and thyroiditis; clinical and/or cytological follow-up are sometimes recommended |
Uncertain/histological*, in need of further evaluation* | Changes that are seen in highly cellular adenomas and follicular carcinomas, including oncocytic variants; corresponds to follicular/oncocytic proliferation or neoplasia; moreover, some of the criteria of other types of malignant tumor may be ‧present, e.g., papillary carcinoma |
Suspect for (non-follicular) malignancy | Changes highly indicative of malignancy, although not all of the corresponding criteria are met |
Positive | Changes meeting the criteria for papillary, medullary, or poorly differentiated thyroid carcinoma, or for other types of cancer |
*two categories in the Bethesda classification (14)