Comparison of mean (±SD) EPA plus DHA amounts (percentage of total fatty acids) between the 9 sample types at 12 mo for the groups who received EPA plus DHA equivalent to 0, 1, 2, and 4 portions of oily fish per week. The dose response in the pools was compared by using a multivariate regression model in which each pool was a component of the outcome, and linearity with dose was assumed. Regression coefficients (slopes) and associated P values for the effect of dose in each pool are shown, and pairwise comparisons between the slopes were made. +Significant difference between adipose tissue and other pools, P < 0.001; *significant difference between plasma phosphatidylcholine and other pools, P < 0.001; #significant difference between platelets and other pools, P < 0.001; £significant difference between nonesterified fatty acids and other pools, P < 0.001.