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. 2012 Jul 2;21(19):4237–4252. doi: 10.1093/hmg/dds247

Table 2.

Small molecules under investigation

Small molecule Known mode of action Used clinically
4-phenylbutyrate Histone deacetylase inhibitor Yes, orally
Trichostatin A Histone deacetylase inhibitor No
Hydroxyurea Ribonucleotide reductase inhibitor Yes, orally
Sulforaphane Phase II detoxification enzyme inducer Yes, clinical trials, orally