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Expression of pS6-S235/236 in the hippocampus of Tsc2cc+ and Tsc2kc+ mice. Immunohistochemistry images are shown for control, Tsc2cc+ and Tsc2kc+ mice at 60 days of age. pS6-S235/236 strongly positive neurons are seen in both Tsc2cc+ and Tsc2kc+ sections. Note the presence of ectopic pS6-S235/236+ cells in the stratum oriens (arrows between cortex and CA1) of both mutants. The scale bar is 200 µm for all images. Hippocampus regions: cornu ammonis 1 (CA1), CA3, dentate gyrus (DG).
