Table 1.

ALS subject characteristics (n=63 unless otherwise noted).

	Central tendency	Range
Age (years)	60.8+/−16.4 (mean+/−SD)	18–90
Gender (female)	52% (n=33)
El Escorial diagnostic classification
Possible ALS	11% (n=7)
Probable ALS	32% (n=20)
Definite ALS	57% (n=36)
Duration of symptoms (years)	3.6+/−3.1 (mean+/−SD)	0.6–17
Bulbar onset	28.6% (n=18)
Family history of ALS	15.9% (n=10)
Forced vital capacity (% predicted)	58+/−27 (mean+/−SD)	8–111
ALS revised functional rating score, current	29 (median)	6–46
Worst bulbar function (FRS-R bulbar)	9 (median)
Rate of functional decline (points/yr)	6.5 (median)	0.3–43.5
Phonemic fluency (F-words), lowest ever (n=54)	10 (median)	4–23
Affective lability (CNS-LS), highest ever (n=60)	10 (median)	7–28