Table I.
Total Population | Other PTCL | CTCL) | |
---|---|---|---|
Characteristic | N (%) or Median (Range) |
N (%) or Median (Range) |
N (%) or Median (Range) |
Number of patients (N) | 37 | 24 | 13 |
Patient Gender | |||
Male | 27 | 18 | 9 |
Female | 10 | 6 | 4 |
Age at Transplant (years) | 40 (7–72) | 39.5 (7–72) | 50 (18–61) |
Donor Type | |||
Sibling | 26 (70.3) | 19 (79.2) | 7 (53.8) |
Matched Unrelated Donor | 11 (29.7) | 5 (20.8) | 6 (46.2) |
Disease Status at Transplant | |||
1st Complete Remission | 3 | 2 | 1 |
2nd Complete Remission | 4 | 4 | 0 |
Partial Remission | 5 | 5 | 0 |
1st Relapse | 7 | 5 | 2 |
Primary Progressive | 1 | 0 | 1 |
Primary Induction Failure | 17 (46.0) | 8 | 9 |
PIT Groups | |||
1 (PIT Score = 0) | NA | 13 (54.2) | NA |
2 (PIT Score = 1) | NA | 2 (8.3) | NA |
3 (PIT Score = 2) | NA | 6 (25.0) | NA |
Unknown | NA | 3 (12.5) | NA |
Prior Regimens | 3 (1–9) | 3 (1–8) | 6 (4–9) |
Months from Diagnosis to Transplant |
17 (4–112) | 11 (4–112) | 38 (9–88) |
Stem Cell Source | |||
Bone Marrow | 5 (13.5) | 4 (16.7) | 1 (7.7) |
Peripheral Blood | 31 (83.8) | 19 (79.2) | 12 (92.3) |
Cord Blood | 1 (2.7) | 1 (4.2) | 0 |
Conditioning Intensity | |||
Reduced | 22 (59.4) | 13 (54.2) | 9 (69.2) |
Non-myeloablative | 2 (5.4) | 1 (4.2) | 1 (7.7) |
Myeloablative | 13 (35.1) | 10 (41.7) | 3 (23.1) |
Conditioning Regimen | |||
Bu | Cy | 1 | 0 | 1 |
FTBI | Cy | 7 | 5 | 2 |
FTBI | Cy | ATG | 1 | 1 | 0 |
FTBI | VP-16 | 4 | 4 | 0 |
Fludarabine | TBI | 2 | 1 | 1 |
Fludarabine | Melphalan | 22 (59.5) | 13 | 9 |
GVHD Prophylaxis | |||
CSA/MMF Based | 20 (54.1) | 12 (50.0) | 8 (61.5) |
Tacro/Siro Based | 17 (45.9) | 12 (50.0) | 5 (38.5) |
MF–mycosis fungoides, SS–Sézary Syndrome, CTCL–cutaneous T-cell lymphoma, DX–diagnosis, Bu–busulfan, CTX–cyclophosphamide, FTBI–fractionated total body irradiation, ATG–anti-thymocyte globulin, VP-16–etoposide, CSA–cyclosporine, MMF–mycophenylate mofetil