Table III.
Overall Survival | |||||||
---|---|---|---|---|---|---|---|
Variable | Reference Group |
Total n= |
Events | Censored | Hazard Ratio |
Confidence Interval |
p-Value |
Age at HCT | Age < 40 | 37 | 17 | 20 | 0.96 | 0.37–2.48 | 0.93 |
PTCL versus CTCL | PTCL | 37 | 17 | 20 | 2.00 | 0.77–5.20 | 0.16 |
Disease Status at HCT | 1CR/2CR/PR | 37 | 17 | 20 | 3.06 | 0.87–10.69 | 0.08* |
PIT Group | 1 / 2 | 21 | 7 | 14 | 1.06 | 0.21–5.50 | 0.94 |
Donor Type | Sibling | 37 | 17 | 20 | 0.96 | 0.34–2.74 | 0.94 |
Conditioning Regimen | RIC | 37 | 17 | 20 | 0.69 | 0.25–1.87 | 0.46 |
aGVHD Max Grade | None-II | 37 | 17 | 20 | 2.17 | 0.49–9.62 | 0.31 |
cGVHD Max Grade | Limited | 23 | 7 | 16 | 0.68 | 0.16–2.88 | 0.60 |
Progression-Free Survival | |||||||
Variable |
Reference Group |
Total n= |
Events | Censored |
Hazard Ratio |
Confidence Interval |
p-Value |
Age at HCT | Age < 40 | 37 | 19 | 18 | 0.94 | 0.38–2.32 | 0.90 |
PTCL versus CTCL | PTCL | 37 | 19 | 18 | 1.56 | 0.62–3.89 | 0.34 |
Disease Status at HCT | 1CR/2CR/PR | 37 | 19 | 18 | 1..80 | 0.65–5.02 | 0.26 |
PIT Group | 1 / 2 | 21 | 9 | 12 | 0.74 | 0.15–3.55 | 0.70 |
Donor Type | Sibling | 37 | 19 | 18 | 0.76 | 0.27–2.10 | 0.59 |
Conditioning Regimen | RIC | 37 | 19 | 18 | 0.58 | 0.22–1.54 | 0.27 |
aGVHD Max Grade | None-II | 37 | 19 | 18 | 1.70 | 0.39–7.43 | 0.438 |
cGVHD Max Grade | Limited | 23 | 9 | 14 | 1.46 | 0.37–5.79 | 0.59 |
Relapse/Progression | |||||||
Variable |
Reference Group |
Total n= |
Events | Censored |
Hazard Ratio |
Confidence Interval |
p-Value |
Age at HCT | Age < 40 | 37 | 9 | 18 | 0.67 | 0.18–2.49 | 0.55 |
PTCL versus CTCL | PTCL | 37 | 9 | 18 | 1.10 | 0.27–4.42 | 0.89 |
Disease Status at HCT | 1CR/2CR/PR | 37 | 9 | 18 | 1.28 | 0.32–5.15 | 0.73 |
PIT Group | 1 / 2 | 21 | 5 | 12 | 0.64 | 0.07–5.74 | 0.69 |
Donor Type | Sibling | 37 | 9 | 18 | 0.27 | 0.03–2.16 | 0.22 |
Conditioning Regimen | RIC | 37 | 9 | 18 | 0.69 | 0.17–2.75 | 0.59 |
aGVHD Max Grade | None-II | 37 | 9 | 18 | 1.00 | 0.00-UND | 0.99 |
cGVHD Max Grade | Limited | 23 | 5 | 14 | 1.98 | 0.28–14.17 | 0.50 |
Univariate Cox proportional hazards analysis:
significance: p ≤0.05;
trend: p ≤ 0.1; Confidence intervals shows 95% confidence ranges. HCT–hematopoietic cell transplant, aGVHD–acute graft-versus-host disease, cGVHD–chronic graft-versus-host disease, PTCL–peripheral T-cell lymphoma, 1CR–first complete remission, 2CR–second complete remission, PR–partial remission, RIC-reduced-intensity conditioning, UND-undetermined.