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Phase III Trials of Idiotype Vaccines in Follicular Lymphoma
| Author | Sponsor | Idiotype Used | Induction Therapy | Response Required | End Point | Results |
|---|---|---|---|---|---|---|
| Levy et al | Genitope | Recombinant | CVP × 8 | CR or PR | PFS | NS |
| Freedman et al | Favrille | Recombinant | Rituximab × 4 | CR, PR, or stable disease | TTP | NS |
| Schuster et al | NCI/Biovest | Hybridoma | PACE to best response, R-CHOP | CR or CRu | DFS | Significant |
