Table 3.

IL-6 Regressed on Chronic Conditions, Indices of Psychological Functioning, and Their Interactions

Predictors	Model 1	Model 2	Model 3
Number of chronic conditions	0.21**	—	0.09*
Purpose in life	0.05	0.04	0.05
Purpose in Life × Number of Chronic Conditions	−0.43*	−0.43*	−0.36*
Positive relations with others	0.10†	0.10†	0.08
Positive Relations With Others × Number of Chronic Conditions	−0.38*	−0.38*	−0.32†
PANAS positive affect	−0.10†	−0.12*	−0.10†
PANAS Positive Affect × Number of Chronic Conditions	−0.03	−0.03	0.08
Life satisfaction	0.02	0.02	0.02
Life Satisfaction × Number of Chronic Conditions	0.01	0.01	−0.01
PANAS negative affect	−0.01	—	0.02
PANAS Negative Affect × Number of Chronic Conditions	0.03	—	−0.08†

Notes. IL-6 = interleukin-6; PANAS = Positive and Negative Affect Scale. Standardized regression coefficients are shown. Separate models were estimated for each psychological measure. Model 1: adjusted for age, sex, race, educational attainment, marital status, sample type, and time between data collections; Model 2: adjusted for Model 1 variables plus PANAS negative affect; and Model 3: adjusted for Model 2 variables plus body mass index, waist–hip ratio, medications, smoking status, alcohol consumption, and physical activity.

†p < .10. *p < .05. **p < .01. ***p < .001.