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. 2012 Sep 11;3:315. doi: 10.3389/fmicb.2012.00315

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Copyright © 2012 Zhu, O’Dell, Ofek, Pancera, Wu, Zhang, Zhang, NISC Comparative Sequencing Program, Mullikin, Simek, Burton, Koff, Shapiro, Mascola and Kwong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.

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Repertoire of donor 39 light-chain variable-domain sequences of IGKV3-15 origin determined by 454 pyrosequencing. After processed by a standard bioinformatics pipeline, 87,229 full-length, light-chain variable-domain sequences from IGKV3-15 germline family are plotted as a function of sequence identity to the light-chain variable-domain of PGT135 (A), PGT136 (B), and PGT137 (C) and of sequence divergence from inferred IGKV3-15 germline allele. Color coding indicates the number of sequences.