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The IFNγ receptor and Jak1, but not PKR, are required for IFNγ-dependent regulation of Stat1-independent genes. Thirty million BMM derived from Stat1−/− mice (A–C), IFNγR−/− mice (A), Jak1−/− and WT mice (B), and PKR−/− × Stat1−/− (C) were incubated with or without IFNγ (14 ng/ml) for different periods of time and mRNA levels corresponding to the indicated genes were determined by Northern analyses.
