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. 2001 Jun 5;98(12):6680–6685. doi: 10.1073/pnas.111163898

Figure 5.

Figure 5

Antiviral responses in Stat1−/− mice. (A) Groups of sex- and age-matched 129/Sv/Ev (n = 58; ○), IFNγR−/− (n = 40; ●), IFNαβR−/− (n = 71; ▾), IFNαβγR−/− (n = 49; ■), or Stat1−/− (n = 79; ▴) mice were infected i.p. with between 0.01 and 5 × 105 plaque-forming units (pfu) of sgMCMV and followed for mortality for 21 days. (B) Groups of sex- and age-matched mice were infected with between 0.01 and 1 × 105 pfu of Sindbis virus s.c. and followed for mortality for 21 days. Data were derived from the following numbers of mice: 129/Sv/Ev (n = 10), IFNγR−/− (n = 38), IFNαβR−/− (n = 57), IFNαβγR−/− (n = 63), and Stat1−/− (n = 89).