Table 1.
Non-synonymous mutations
| Position* | Ref | Obs | A | C | G | T | total | used | SNP Type | Gene ID (ENSRNOG) | Name | Description | cDNA | Prot | AA change |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 63385139 |
G |
AG |
339 |
1 |
314 |
0 |
714 |
654 |
het2 |
00000006674 |
Fam101b |
Protein FAM101B |
647 |
176 |
P- > L |
| 64469050 |
C |
T |
0 |
0 |
0 |
392 |
393 |
392 |
hom |
00000012866 |
Nek8 |
serine/threonine-protein kinase Nek8 |
2008 |
650 |
R- > C |
| 66106990 |
T |
TA |
25 |
0 |
0 |
32 |
152 |
57 |
het1 |
00000022699 |
LOC303341 |
Keratin, type I cytoskeletal 18 |
464 |
155 |
Y- > F |
| 66106991 | A | AT | 32 | 0 | 0 | 28 | 155 | 60 | het1 | 00000022699 | LOC303342 | Keratin, type I cytoskeletal 19 | 463 | 155 | Y- > N |
List of non-synonymous mutations derived from Nimblegen array target sequencing and bounded by the genes Myo1c and Slc6a4 and using the flanking markers D10Rat161 and D10Rat238 [62685555-67091740].
*Position location in base pairs (bp) was determined using the Rat Genome Browser Gateway using the Baylor 3.4/ build rn4 (http://genome.ucsc.edu/cgi-bin/hgGateway?org=rat). Ref: nucleotide on the ref sequence. Obs: nucleotide recorded from transcripts. A C G T: number of transcripts recorded with a change to the reference. Total: total number of transcripts recorded with a change to the reference. Used: reads that support the change after consideration of read quality. SNP type: defines type of mutation. DNA: position of the base change within the cDNA. prot: position of the amino acid change within the protein. AA change: resultant change of amino acid in the protein. Hom: homozygous. Het: heterozygous.