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. 2012 Aug 10;7:4861–4872. doi: 10.2147/IJN.S34770

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© 2012 Hu et al, publisher and licensee Dove Medical Press Ltd.

This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.

PMC Copyright notice

Fluorescent intensity according to flow cytometry data, elucidating the effect of charge modifications on the internalization efficiency of positively charged FITC-BSA-loaded ChS-CS nanoparticles ( ), negatively charged FITC-BSA ChS-CS nanoparticles ( ), and FITC-BSA solution (0.1 mL; 0.1 mg/mL) ( ) on Caco-2 cells at varied time incubations.

Note: Results are represented as the mean ± standard deviation, n = 6.

Abbreviations: BSA, bovine serum albumin; ChS, chondroitin 4-sulfate sodium salt; CS, chitosan; FITC, fluorescein isothiocyanate.

Inline graphic — Fluorescent intensity according to flow cytometry data, elucidating the effect of charge modifications on the internalization efficiency of positively charged FITC-BSA-loaded ChS-CS nanoparticles ( ), negatively charged FITC-BSA ChS-CS nanoparticles ( ), and FITC-BSA solution (0.1 mL; 0.1 mg/mL) ( ) on Caco-2 cells at varied time incubations.

Note: Results are represented as the mean ± standard deviation, n = 6.

Abbreviations: BSA, bovine serum albumin; ChS, chondroitin 4-sulfate sodium salt; CS, chitosan; FITC, fluorescein isothiocyanate.