Table 3.
Values of correlation (‘r’) of parasitological and clinical parameters with survival of animals subjected to different treatment schemes using biotherapic (BIOTTc17dH)
|
‘r’ FOR CORRELATION | |||
|---|---|---|---|
| PARAMETERS | CI | BIOTPI | BIOT4PI |
| AUC |
(-)0.2250 |
(-)0.1980 |
(-)0.2349 |
| Ptotal |
(-)0.3220 |
(-)0.4387 |
(-)0.5227 |
| Pmax |
(-)0.2989 |
(-)0.3182 |
(-)0.5350 |
| Day Pmax |
NS |
NS |
NS |
| PPP |
(+)0.4825 |
(+)0.6704 |
(+)0.9995 |
| PP |
(+)0.7901 |
(-)0.7000 |
(-)0.8998 |
| Ta |
NS |
NS |
NS |
| WEIGHT |
NS |
NS |
(+)0.4797 |
| WATER | NS | NS | NS |
NS = no significant correlation. ‘r’ values are presented for significant correlations (p < 0.05) between survival and the parameters: AUC = area under the curve (parasites/mL); Ptotal – total parasitemia (parasites/ mL); Pmax = maximum peak of parasites (parasites/ mL); Day of Pmax- Day of maximum peak of parasites; PPP = Prepatent period; PP = patent period; Ta = Temperature; Weight and Water. Groups: CI: control group – infected animals treated with 7% ethanol-water solution diluted in water (10μL/mL) offered ad libitum; BIOTPI: infected animals treated with biotherapic BIOTTc17dH diluted in water (10μL/mL) offered ad libitum from the day of the infection until the death of the animals; BIOT4PI: infected animals treated with biotherapic BIOTTc17dH diluted in water (10μL/mL) offered ad libitum from the 4th day of the infection until the death of the animals.