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. 2012 Jun 21;10:130. doi: 10.1186/1479-5876-10-130

Table 3.

Prognostic factors of septic patients at the emergency room

  Non-survivors n = 11 Survivors n = 56 Crude OR (95% CI) p value Adjusted OR (95% CI) p value
Age (y) (mean±SD)
69.6±9.7
63.5±14.1
 
0.09
 
 
Male/Female
8/3
36/20
0.68(0.16-2.84)
0.74
-
-
Underlying diseases [n (%)]
 
 
 
 
 
 
Diabetes mellitus
5 (8)
19 (28)
0.62 (0.17-2.28)
0.51
-
-
Hypertension
5 (8)
25 (37)
0.97 (0.26-3.55)
1.00
-
-
Liver diseases/alcoholism
3 (5)
8 (12)
0.44 (0.97-2.04)
0.37
-
-
Chronic obstructive pulmonary disease
2 (3)
6 (9)
0.54 (0.09-3.11)
0.61
-
-
Stroke
3 (5)
9 (13)
0.51 (0.11-2.30)
0.40
-
-
Coronary artery disease
0 (0)
8 (12)
0.81 (0.72-0.92)
0.34
-
-
Cancer
4 (6)
10 (15)
0.38 (0.09-1.55)
0.22
-
-
Connective tissue disease
0 (0)
1 (2)
0.83 (0.75-0.93)
1.00
-
-
Chronic renal disease
0 (0)
3 (5)
0.83 (0.74-0.93)
1.00
-
-
Glasgow coma score (mean±SD)
13.1±2.4
12.7±3.7
 
0.76
 
 
Shock within 24 hours [n (%)]
7 (11)
37 (56)
1.18 (0.30-4.54)
1.00
-
-
Ventilator treatment within 24 hours [n (%)]
8 (12)
16 (24)
0.15 (0.04-0.64)
0.013
-
-
Disease severity index (mean±SD)
 
 
 
 
 
 
Maximum 24-h APACHE II score
20.9±3.8
18.9±6.9
 
0.36
 
 
Charlson Co-morbidity Index score
4.2±2.8
2.9±2.8
 
0.18
 
 
Maximum 24-h SOFA score
7.5±1.8
5.6±2.9
 
0.04
 
 
Laboratory data on admission
 
 
 
 
 
 
Mean (SD) white blood cells (×109/L)
16.9 (12.6)
15.7 (10.4)
 
0.72
 
 
Mean (SD) Hemoglobin(mg/dL)
12.7 (2.7)
11.8 (2.1)
 
0.24
 
 
Mean (SD) Platelet (×104/L)
114.0 (55.6)
166.9 (98.3)
 
0.09
 
 
Mean (SD) C-reactive protein (mg/dL)
161.8 (107.0)
195.7 (128.2)
 
0.42
 
 
Mean (SD) Glucose (mg/dL)
251.4 (218.8)
167.5 (94.5)
 
0.24
 
 
Mean (SD) Creatinine (mg/dL)
1.7 (0.6)
2.2 (1.6)
 
0.36
 
 
Mean (SD) Lactate (mmol/L)
62.5 (48.2)
30.2 (13.8)
 
<0.001
 
 
Mean (SD) Procalcitonin(mg/dL)
18.1 (16.4)
34.0 (52.9)
 
0.33
 
 
Mean (SD) B-type natriuretic peptide (pg/ml)
776.3 (422.4)
679.5 (523.9)
 
0.79
 
 
Median (IQR) plasma nuclear DNA (ng/mL)
2240 (1040–4760)
400 (210–886)
 
<0.001
0.094
1.0 (0.99-1.0)
Median(IQR) plasma mitochondrial DNA (ng/mL) 520 (218–846) 121 (69–227)   <0.001 0.015 0.99 (0.99-0.999)

Abbreviations: SD, standard deviation; IQR, inter-quartile range; APACHE, Acute Physiology and Chronic Health Evaluation; SOFA, Sequential Organ Failure Assessment.