Table 2.
Variable Initial/ follow-up visit |
Progression Group (n = 198) | Non-progression Group (n = 168) | p value |
---|---|---|---|
Fasting glucose (mmol/L) |
6.15 ± 1.81 |
5.49 ± 1.25 |
<0.001 |
7.84 ± 1.80 |
5.30 ± 1.22 |
0.005 |
|
OGTT (mmol/L) |
10.09 ± 4.17 |
8.65 ± 3.41 |
<0.001 |
9.68 ± 3.79 |
8.47 ± 3.38 |
0.002 |
|
Fasting insulin (mU/L) |
13.50 ± 26.58 |
12.57 ± 27.04 |
0.010 |
14.43 ± 19.01 |
17.10 ± 60.81 |
0.002 |
|
Postprandial insulin (mU/L) |
78.31 ± 117.74 |
62.43 ± 65.86 |
0.388 |
80.27 ± 71.31 |
88.35 ± 107.35 |
0.868 |
|
Bennett index |
1.79 ± 0.65 |
0.41 ± 0.56 |
<0.001 |
|
0.95 ± 0.84 |
0.67 ± 0.95 |
<0.001 |
HbA1c (%) |
6.73 ± 1.40 |
6.24 ± 0.98 |
0.001 |
6.79 ± 1.53 |
6.07 ± 0.78 |
<0.001 |
|
hsCRP (mg/L) |
9.28 ± 13.56 |
13.34 ± 22.51 |
0.600 |
6.55 ± 12.01 |
2.68 ± 4.14 |
0.048 |
|
BUN (mmol/L) |
5.44 ± 1.59 |
5.45 ± 1.50 |
0.941 |
6.06 ± 1.90 |
5.70 ± 1.48 |
0.623 |
|
Creatinine (umol/L) |
84.47 ± 18.34 |
89.90 ± 36.51 |
0.671 |
93.11 ± 23.46 |
87.28 ± 18.87 |
0.585 |
|
Urine acid (umol/L) |
339.83 ± 76.41 |
339.30 ± 85.77 |
0.878 |
358.38 ± 81.25 |
362.80 ± 79.00 |
0.966 |
|
Urine Ma/Cr |
12.12 ± 49.70 |
3.65 ± 18.74 |
0.011 |
16.00 ± 69.94 |
2.09 ± 3.14 |
0.366 |
|
GFR (ml/min) |
80.16 ± 25.46 |
76.62 ± 28.98 |
0.345 |
73.52 ± 25.48 |
71.55 ± 23.33 |
0.049 |
|
Serum triglyceride (mmol/L) |
2.13 ± 1.72 |
1.86 ± 2.01 |
0.072 |
1.76 ± 1.34 |
1.65 ± 1.50 |
0.207 |
|
Serum cholesterol (mmol/L) |
4.58 ± 1.22 |
4.18 ± 1.09 |
0.103 |
2.08 ± 0.76 |
2.05 ± 0.78 |
0.412 |
|
HDL (mmol/L) |
1.05 ± 0.23 |
1.05 ± 0.26 |
0.706 |
1.06 ± 0.26 |
1.14 ± 0.26 |
0.246 |
|
LDL (mmol/L) |
2.81 ± 0.96 |
2.45 ± 0.84 |
0.118 |
2.08 ± 0.76 |
2.05 ± 0.78 |
0.412 |
|
Lpa (mmol/L) |
0.21 ± 0.21 |
0.20 ± 0.18 |
0.941 |
0.21 ± 0.17 |
0.30 ± 0.49 |
0.317 |
|
ApoA (mmol/L) |
1.13 ± 0.22 |
1.12 ± 0.20 |
0.764 |
1.11 ± 0.22 |
1.12 ± 0.29 |
0.738 |
|
ApoB (mmol/L) |
0.93 ± 0.28 |
0.87 ± 0.26 |
0.342 |
0.80 ± 0.25 |
0.77 ± 0.23 |
0.225 |
|
Ejection Fraction |
62.50 ± 9.06 |
64.01 ± 6.86 |
0.331 |
62.62 ± 8.38 | 62.62 ± 8.20 | 0.153 |