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Differential influence of Cdk2 loss on OPC
| Physiological condition | Pathological condition | |||
|---|---|---|---|---|
| |
SVZ |
CC |
SVZ |
CC |
|
Proliferation |
↓ |
NO |
↓ |
↓ |
|
Differentiation |
↑ |
NO |
↑ |
↑ |
| Myelination/ remyelination | NC | NO | NC | ↑ |
The pathological condition concerns corpus callosum LPC-induced demyelination. SVZ subventricular zone; CC corpus callosum; NO not observed; NC not concerned
