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. 2012 Sep 13;8(9):e1002664. doi: 10.1371/journal.pcbi.1002664

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© 2012 Yu et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Equilibrium activation values (m³, and m ) of co-existing intact Nav and CLS Nav channels plotted as a function of V_m. Black solid and black dashed line represent m³ for intact and 20 mV CLS channels with f = 1. For a membrane with large Nav-CLS injury given by: LS_i = [0,20]mV and f_i = [0.3,0.7], the gray bold line denotes . Red line: m of the intact channels.

Inline graphic — Equilibrium activation values (m³, and m ) of co-existing intact Nav and CLS Nav channels plotted as a function of V_m. Black solid and black dashed line represent m³ for intact and 20 mV CLS channels with f = 1. For a membrane with large Nav-CLS injury given by: LS_i = [0,20]mV and f_i = [0.3,0.7], the gray bold line denotes . Red line: m of the intact channels.