Table 3.

The distribution of NOD2 genotypes in patients with inflammatory bowel disease (IBD), Crohn’s disease (CD), ulcerative colitis (UC) and in controls (HC) [n(%)]

NOD2 genotype frequency n (%)
Group	WT/WT	Heterocygotes	Homocygotes
IBD (n = 278)
R702W	241 (86.7)	34 (12.2)	3 (1.1)
G908R	273 (98.2)	5 (1.8)	0 (0.0)
1007 fs	263 (94.6)	15 (5.4)	0 (0.0)
CD (n = 173)
R702W	145 (83.8)	26 (15.0)	2 (1.2)
G908R	168 (97.1)	5 (2.9)	0 (0.0)
1007 fs	158 (91.3)	15 (8.7)*	0 (0.0)
UC (n = 105)
R702W	96 (91.4)	8 (7.6)	1 (1.0)
G908R	105 (100.0)	0 (0.0)	0 (0.0)
1007 fs	105 (100.0)	0 (0.0)	0 (0.0)
HC (n = 188)
R702W	171 (91.0)	17 (9.0)	0 (0.0)
G908R	186 (98.9)	2 (1.1)	0 (0.0)
1007 fs	183 (97.3)	5 (2.7)	0 (0.0)

WT: Wild-type

^* 1007 fs allele frequency, CD versus UC (p = 0.021) and CD versus controls (p = 0.0135).