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. 2012 Jun 28;4:6. doi: 10.1186/1757-4749-4-6

Table 3.

The distribution of NOD2 genotypes in patients with inflammatory bowel disease (IBD), Crohn’s disease (CD), ulcerative colitis (UC) and in controls (HC) [n(%)]

NOD2 genotype frequency n (%)
Group
WT/WT
Heterocygotes
Homocygotes
IBD (n= 278)
 R702W
241 (86.7)
34 (12.2)
3 (1.1)
 G908R
273 (98.2)
5 (1.8)
0 (0.0)
 1007 fs
263 (94.6)
15 (5.4)
0 (0.0)
CD (n= 173)
 R702W
145 (83.8)
26 (15.0)
2 (1.2)
 G908R
168 (97.1)
5 (2.9)
0 (0.0)
 1007 fs
158 (91.3)
15 (8.7)*
0 (0.0)
UC (n= 105)
 R702W
96 (91.4)
8 (7.6)
1 (1.0)
 G908R
105 (100.0)
0 (0.0)
0 (0.0)
 1007 fs
105 (100.0)
0 (0.0)
0 (0.0)
HC (n= 188)
 R702W
171 (91.0)
17 (9.0)
0 (0.0)
 G908R
186 (98.9)
2 (1.1)
0 (0.0)
 1007 fs 183 (97.3) 5 (2.7) 0 (0.0)

WT: Wild-type

* 1007 fs allele frequency, CD versus UC (p = 0.021) and CD versus controls (p = 0.0135).