Table 4. Distribution of KIR genotype groups in patients with and without acute graft rejection.
| Genotype | KIR | Pts with AGR | Pts without AGR | |||||||||||||
| No. | 2DL1 | 2DL2 | 2DL3 | 2DS1 | 2DS2 | 2DS3 | 2DS4 fl | 2DS4 del | 2DS5 | 3DL1 | 3DS1 | N | % | N | % | |
| 1 | AA/2DS4fl− | + | − | + | − | − | − | − | + | − | + | − | 14 | 21.9 | 50 | 78.1 |
| 2 | AA/2DS4fl+ | + | − | + | − | − | − | + | + | − | + | − | 11 | 50.0 | 11 | 50.0 |
| 3 | BX | 68 | 34.5 | 129 | 65.5 | |||||||||||
Differences between frequencies of three genotype groups: χ2 = 6.675, df = 2, p = 0.035.
Abbreviations: AA, homozygote for the killer immunoglobulin-like receptor A haplotype (for a definition of A and B haplotypes, see Introduction); AGR, acute graft rejection; BX, a group of the killer immunoglobulin-like receptor genotypes containing at least one B haplotype; as they contain different combinations of KIR genes, the presence or absence of particular genes could not been shown here; KIR, killer immunoglobulin-like receptor; KIR2DS4fl, KIR2DS4 full length gene; KIR2DS4del, KIR2DS4 22-base pair deletion variant of the KIR2DS4 gene; Pts, patients.