Table 2. Cytokine concentrations in peritoneal dialysates.
Group 1 (Control) | Group 2 (B only) | Group 3 (F only) | Group 4 (B+F) | Group 5 (B+F+PTX) | |
VEGF (pg/ml) | 2.7±0.8 | 11.1±2.0 | 12.0±2.4 | 93.2±16.2* | 10.0±1.8† |
TGFβ (pg/ml) | 111±21 | 206±28 | 118±16 | 1277±275* | 216±38† |
IL-1β (pg/ml) | 27±11 | 149±21* | 34±8 | 381±38* | 87±10† |
TNFα (pg/ml) | 371±76 | 1880±160* | 302±69 | 2530±526* | 470±135† |
IL-6 (pg/ml) | 235±50 | 1780±242* | 380±93 | 4850±1230* | 418±4† |
PAI-1 (ng/ml) | 13±2 | 108±13* | 53±9* | 175±26* | 21±4† |
tPA (pg/ml) | 5±1 | 79±15* | 48±11* | 118±23* | 56±13* |
Data are expressed as mean ± SEM. PBS, phosphate buffered saline; B, bacteria; F, fibrinogen; PTX, pentoxifylline.
P<0.05 vs. Group 1,
P<0.05 vs. Group 4.