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. 2001 May 22;98(12):6698–6703. doi: 10.1073/pnas.111092198

Figure 6.

Figure 6

Enlarged hypertrophic zone in Sox9+/− epiphyseal growth plate of the proximal tibia. (A and B) Alcian blue staining of the epiphyseal growth plates of wild-type (A) and Sox9+/− (B) embryos at E18.5. (C–J) RNA in situ hybridization analysis of the expression of Col10a1 (E and F), parathyroid hormone receptor (PTHrP-R; G and H), and Indian hedgehog (Ihh; I and J) in the tibia epiphyseal growth plates of wild-type (C, E, G, and I) and Sox9+/− (D, F, H, and J) neonates. (C and D) Bright field. H, hypertrophic zone.