Table 1.
List of significant proteins showing more than twofold altered protein expression within UC patients
Spot | Protein Name | SwissProt Acc. no. | S cov %1 | pI2 | Mw2 | Fold diff.3 | T -test (p)4 |
---|---|---|---|---|---|---|---|
Higher level in RE | |||||||
1 |
Glycerol-3-phosphate-dehydrogenase |
P04406 |
6a |
9.3 |
36 |
3.30 |
1.388e-005 |
25 |
B-cell antigen receptor complex-associated protein beta chain |
P40259 |
42 |
5.6 |
26 |
3.05 |
3.776e-004 |
3 |
Annexin A6 |
P08133 |
41a |
5.3 |
76 |
2.81 |
1.626e-006 |
4 |
Glycerol-3-phosphate-dehydrogenase |
P04406 |
37a |
9.3 |
36 |
2.70 |
6.178e-005 |
5 |
Plasma-cell induced resident endoplasmatic reticulum protein |
Q8WU39 |
52a |
5.3 |
21 |
2.61 |
4.785e-005 |
65 |
Actin cytoplasmic |
P60709 |
42a |
5.5 |
41 |
2.45 |
1.049e-006 |
7 |
Alpha enolase |
P06733 |
35a |
7.7 |
47 |
2.42 |
5,889e-005 |
8 |
L-lactate dehydrogenase B-chain |
P07195 |
46a |
5.7 |
37 |
2.40 |
4.021e-005 |
9 |
Tubulin beta 5-chain |
P07437 |
41a |
4.6 |
50 |
2.18 |
1.801e-004 |
Lower level in RE | |||||||
10 |
Alpha-enolase |
P06733 |
44a |
7.7 |
47 |
3.70 |
1.403e-008 |
11 |
Hydroxymethylglutaryl–CoA synthase |
P54868 |
28a |
9.2 |
57 |
2.94 |
2.448e-009 |
12 |
Selenium binding protein |
Q13228 |
42a |
5.9 |
53 |
2.50 |
3.770e-007 |
13 |
Carbonic anhydrase 2 |
P00918 |
60a |
7.0 |
29 |
2.33 |
8.325e-007 |
14 | Selenium binding protein | Q13228 | 60a | 5.9 | 53 | 2.08 | 5.508e-006 |
1Percentage sequence coverage (S cov %) is followed by a if the mascot score was significant (P < 0.05). 2Isoelectric point (pI) and molecular weight (Mw) are presented as theoretical values. 3Fold difference in protein level. 4p-value from t-test. 5Spot location on the gel differs from the theoretical molecular mass. 6The protein was identified by MS/MS.