Table 3.
Biological processes associated with identified proteins with references to results obtained in earlier studies
| Biological process | Protein name |
|---|---|
| Energy generation |
triosephosphate isomerase1,3,4, glycerol-3-phosphate-dehydrogenase, alpha enolase2,3, isocitrate dehydrogenase, L-lactate dehydrogenase B-chain, inorganic pyrophosphatase, enoyl-CoA hydratase |
| Response to oxidative stress |
selenium binding protein1,2, superoxide dismutase, thioredoxin-dependent peroxide reductase1, peroxiredoxin-14, peroxiredoxin-4, peroxiredoxin-6 |
| Stress response proteins | Alpha-enolase3, Hsp601,3, Hsp701,4 |
1Different protein level between diseased UC versus normal colon mucosa tissues using colon biopsies [22]. 2Different protein level between inflamed and non-inflamed tissue regions in single UC patients as identified in purified epithelial cells from biopsies [19]. 3Different protein level in mucosal tissue biopsies from patients with chronic refractory pouchitis before and after antibiotic/probiotic therapy [34]. 4Different protein level between intestinal epithelial cells from healthy subjects and CD patients [35].