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. 2012 Sep 13;7(9):e41804. doi: 10.1371/journal.pone.0041804

Figure 5. Amex-Jag1 expression in regenerating axolotl limb.

Figure 5

Longitudinal tissue section of a 17 dpa regenerating limb immunostained with human Jagged1 antibody. A. Higher Jagged1 immunoreactivity (red) is detected in the stump tissue proximal to the animal body (down) than in the mid-bud blastema area (up). White dashed line indicates amputation plane. B. A magnification of the blastema area enclosed in yellow dashes shows how Jag1 immunoreactivity is scarce in mid-bud blastema. C. Strong Jag1 immunoreactivity is detected in the membrane of epidermal cells in non-regenerating stump. Cell nuclei have been stained with DAPI (blue) present in the mounting media.