Table 4. Stratification for the test of heterogeneity on XPD Asp312Asn based on a recessive model.
Q-test | I2, % | τ2 | OR(95%CI) | P value | |||
chi-squared | d.f. | p | |||||
Overall | 9.91 | 8 | 0.272 | 19.2 | 0.0354 | 1.48 (1.12–1.97) | 0.007 |
Asians | 4.58 | 5 | 0.470 | 0.0 | 0.0000 | 1.77 (1.19–2.63) | 0.005 |
Caucasians | 3.43 | 2 | 0.180 | 41.6 | 0.0587 | 1.31 (0.86–1.99) | 0.211 |
Large sample | 5.42 | 3 | 0.144 | 44.6 | 0.1053 | 1.35 (0.82–2.21) | 0.239 |
Small-and-moderate sample | 2.71 | 4 | 0.607 | 0.0 | 0.0000 | 1.74 (1.18–2.56) | 0.005 |
High quality | 8.55 | 5 | 0.128 | 41.5 | 0.0948 | 1.56 (1.05–2.33) | 0.028 |
Low-and-moderate quality | 1.36 | 2 | 0.508 | 0.0 | 0.0000 | 1.42 (0.85–2.40) | 0.184 |
High quality Asians | 1.68 | 2 | 0.433 | 0.0 | 0.0000 | 2.37 (1.29–4.36) | 0.005 |
High quality Caucasians | 3.43 | 2 | 0.180 | 41.6 | 0.0587 | 1.31 (0.86–1.99) | 0.211 |
Publication before or in 2007 | 4.34 | 3 | 0.227 | 30.9 | 0.1128 | 1.61(0.89–2.92) | 0.115 |
Publication after 2007 | 5.41 | 4 | 0.248 | 26.0 | 0.0452 | 1.46 (1.02–2.09) | 0.041 |
Cardia type | 0.85 | 2 | 0.654 | 0.0 | 0.0000 | 0.89 (0.56–1.43) | 0.642 |
PCR-RFLP genotyping | 6.59 | 4 | 0.159 | 39.3 | 0.1474 | 1.90 (1.09–3.31) | 0.023 |
Direct sequencing | 0.02 | 1 | 0.902 | 0.0 | 0.0000 | 1.24 (0.70–2.20) | 0.450 |
Only D+L ORs (95% CI) and P values of D+L estimates provided.