Figure 1. Partial pressure of oxygen in tissue (PtO₂) measurements in brain parenchyma and capillary density data showing increased oxygen delivery after acclimation. A.

Brain (cortex) PtO₂ measurements from the same animals both pre- and post-acclimation (n = 5, mean±S.D. paired t-test comparing pre- and post-acclimation, p<0.05). B. Capillary length per area of cortex before and after acclimation C. Capillary length per volume of cortex before and after acclimation. Measurements are from the dorsolateral cortex in the CA4-CA5 region and show the increased capillary density associated with acclimation to hypoxia. Control, non-acclimated subjects are compared with acclimated subjects (mean±S.D., *p<0.05, **p<0.005).