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. 2004 Feb;24(4):1595–1607. doi: 10.1128/MCB.24.4.1595-1607.2004

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Copyright © 2004, American Society for Microbiology

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FIG. 8. — Chromosomal instability in wild-type, PARP-2^+/−, and PARP-2^−/− primary MEFs. (Upper panel) Frequency of the indicated chromosomal aberrations per metaphase in the indicated number of metaphases in wild-type, PARP-2^+/−, and PARP-2^−/− primary MEFs. In parentheses is the number of aberrations in the total number of metaphases. The percentage of undetectable telomeric signals out of the total number of telomeres analyzed is also indicated. (Lower panel) Representative images of a chromosome break (A1), a signal-free end (as indicated by an arrow in A2), and an end-to-end Robertsonian-like fusion (A3).