Table 1.

Immunohistochemical characterization of epidermal and oral mucosal derived ePUKs

MARKER	Epidermal1 ePUKs	Oral mucosal2 ePUKs	FUNCTION
Ki 673	66 ± 8%	25 – 50%	cell cycle related nuclear protein expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase) but absent in resting (G0) cells
P634	64 ± 0%	20 – 75%	expressed in the epithelial basal cells of different organs and have been considered as possible markers of stem cells/reserve cells
K145	75 ± 8	50 – 100%	expressed in basal cells of epithelium
K105	16 ± 6%	20 – 30%	seen in all suprabasal cell layers including stratum corneum
loricrin	4 ± 2%6	0%7	major protein component of the cornified cell envelope found in terminally differentiated epidermal cells but not oral non-keratinized mucosal cells
involucrin8	88 ± 6 but very light and diffuse	100% light and diffuse	Found in terminally differentiated keratinocytes
α6β4integrin9	trace	Trace	α6 β4 complex receptor for laminin and It is expressed on epithelial basal cells
CD717	trace	0%	α6 β4integrinbright/CD71dim is reported to be a marker of epithelial stem cells

¹Mean ± SEM, N = 4.

²N = 2, range.

³Knagg et al (1994) [16].

⁴Pellegrini et al (2001) [17].

⁵Lane et al (2004) [18].

⁶Mehrel et al (1990) [19].

⁷Lee et al (2000) [20].

⁸Watt et al (1981) [22].

⁹Webb et al (2004) [21].