Table 3. Complications and outcome in adults with vs. without intracranial hemorrhagic complicating bacterial meningitisa.
| Characteristic | Episodes with Brain Hemorrhage (n = 24) | Episodes without Brain Hemorrhage (n = 836) | p-value |
| Complications | |||
| Impairment of consciousness | 23/24 (96) | 447/825 (54) | <0,001 |
| Focal neurologic deficits | 11/20 (56) | 163/796 (21) | <0.001 |
| Systemic complicationsb | 20/24 (83) | 302/824 (37) | <0.001 |
| Glasgow Outcome Scale | |||
| 1. Death | 15/24 (63) | 129/836 (15) | <0.001d |
| 2. Vegetative state | 0/24 | 1/836 (0.1) | 0.99d |
| 3. Severely disabled | 2/24 (8) | 35/836 (4) | 0.561d |
| 4. Moderately disabled | 6/24 (25) | 116/836 (14) | 0.135d |
| 5. Good recovery | 1/24 (4) | 555/836 (66) | <0.001d |
| Neurologic sequelae | 7/9 (78)c | 99/707 (14) | <0.001d |
a
Data are number/number evaluated (%).
b
Systemic complications included respiratory failure and circulatory shock (58% and 67%, respectively).
c
Neurologic sequelae in patients with intracranial hemorrhage include hemiparesis (4), cognitive impairment (3), cranial nerve palsy (3) and ataxia (3).
d
Fisher exact test.